Lexus RX 350vsMercedes-Benz E350
Mercedes-Benz E350 leads in City MPG (25 vs 22) and Highway MPG (33 vs 29) and 3 more.
Fuel Economy
22
City MPG
25
29
Highway MPG
33
25
Combined MPG
28
Engine & Drivetrain
4
Cylinders
4
2
Engine Displacement
2
FWD
Drive Type
RWD
Automatic
Transmission
Automatic
Premium Gasoline
Fuel Type
Premium Gasoline
Emissions & Cost
354
CO₂ Emissions
316
2,750
Annual Fuel Cost
2,450
Small Sport Utility Vehicle 2WD
Vehicle Class
Midsize Cars
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Data sourced from EPA Fuel Economy Data (Public Domain (U.S. Government)).