Audi A5 quattrovsMercedes-Benz E350 4matic
Mercedes-Benz E350 4matic leads in City MPG (24 vs 22) and Highway MPG (33 vs 32) and 3 more.
Fuel Economy
22
City MPG
24
32
Highway MPG
33
26
Combined MPG
27
Engine & Drivetrain
4
Cylinders
4
2
Engine Displacement
2
AWD
Drive Type
AWD
Automatic
Transmission
Automatic
Premium Gasoline
Fuel Type
Premium Gasoline
Emissions & Cost
345
CO₂ Emissions
327
2,650
Annual Fuel Cost
2,550
Midsize Cars
Vehicle Class
Midsize Cars
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Data sourced from EPA Fuel Economy Data (Public Domain (U.S. Government)).